Health Condition 1: 8- Other Procedures
Conditions
Interventions
Intervention1: Induction Agents: to evaluate and compare the effectiveness of propofol versus ketofol as an induction agent on the haemodynamic profile in lumbar spine surgery under general anaesthesi
Sponsors
Department of Anaesthesiology SMS Medical college and attached HospitalsJaipur India
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients posted for elective spine surgery under general anaesthesia 2.Patients belonging to ASA grade I and II 3.Patients willing to consent 4.Patients of either sex,between the age group 20-60 years.
Exclusion criteria
Exclusion criteria: 1.Obesity(BMI.30KG/m. 2.Difficukt laryngoscopy and intubation. 3.Pregnant and lactating females. 4.Patients with known hypersensitivity or contra-indications to study drugs. 5.Patients having cardiorespiratory dysfunction or renal,hepaticor metabolic disturbances, any chronic disease hypertension,diabetes mellitus, history of epilepsy and history of psychiatric illness. 6.Patient with a history of sore throat or upper respiratory tract infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Comparing the magnitude of haemodynamic variables(HR,SBP,DBP,MBP) in propofol versus ketofol study groups.Timepoint: Baseline,at 1 min. after induction, at 1 min. at 2,3,4,5,10,15,20,25,30 min. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Comparing the changes in rate pressure product and perfusion index in both study group. 2.Comparing the modified alderate score after extubation in both study groups. 3.Comparing the incidence of postoperative nausea and vomiting and shivering in both study groups.Timepoint: Baseline , at 1 min. after induction, at 1 min. at 2,3,4,5,10,15,20,25,30 min. | — |
Countries
India
Contacts
Public ContactDr Vijeta
SMS Medical College and attached Hospitals,Jaipur
Outcome results
None listed