Homoeopathic mother tincture to regulate blood glucose levels of type 2 diabetes mellitus patients.

Role of four preidentified homoeopathic mother tinctures in regulation of glucose homeostasis, oxidative stress and metabolic enzymes in type 2 diabetes mellitus patients: an exploratory, double-blind, stratified, randomized controlled trial based on symptom cluster approach - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/108007

Enrollment

192

Registered

2026-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Homoeopathic mother tincture: Cluster 1. Mother tincture of Syzygium jambolanum Cluster 2. Mother tincture of Cephalandra indica Cluster 3. Mother tincture of Gymnema sylvestre Cluster

Eligibility

Inclusion criteria

Inclusion criteria: 1. Freshly diagnosed cases or patients diagnosed to be suffering from T2DM for not more than one year. 2. T2DM patients with FPG levels between 126 mg/dL and 220 mg/dL. 3. Patients who are not taking any medicines (allopathic, Ayush or any other treatment) for T2DM. 4. Patients willing to give informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with any comorbid conditions like other noncommunicable diseases or systemic illness. 2. Patients with serious psychiatric disorders like panic attacks, suicidality, Alzheimer s, Schizophrenia. 3. Patients who are taking any kind of supplements or natural plant extracts. 4. Patients doing high-intensity exercise. 5. Patients with pregnancy or planned pregnancy during the time period of the study.

Design outcomes

Primary

Measure	Time frame
The primary outcome is to investigate the antioxidant potential of four preidentified homoeopathic MTs and to clinically correlate their effect on HbA1C, metabolic enzymes and mitochondrial homeostasis in T2DM patients.Timepoint: Baseline and third-month. Mitochondrial homeostasis at baseline, one month, and three months.	—

Secondary

Measure	Time frame
To assess the change in blood glucose profile, inflammatory markers of T2DM patients and to establish the safety profile of four preidentified homoeopathic mother tincturesTimepoint: Baseline and third-month.	—

Countries

India

Contacts

Public ContactDr Varanasi Roja

Central Research Institute (Homoeopathy), Lucknow

dramit911@gmail.com9140577532

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026