Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 45 to 80 years of either gender undergoing elective unilateral primary total knee arthroplasty under spinal anesthesia ASA physical status one to three able to understand visual analog scale willing to give written informed consent and comply with study protocol and follow up
Exclusion criteria
Exclusion criteria: Refusal to participate allergy to local anesthetic or study drugs infection at block site coagulopathy or anticoagulation severe hepatic renal or cardiac disease neurological disorder affecting lower limb cognitive impairment or psychiatric illness chronic opioid use more than three months revision or bilateral knee arthroplasty conversion to general anesthesia intraoperative complications requiring protocol deviation participation in another clinical trial within past 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain score using visual analog scale at rest and on movementTimepoint: At 2 hours 6 hours 12 hours and 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Total opioid consumption in first 24 hoursTimepoint: Within 24 hours postoperatively;Time to first rescue analgesiaTimepoint: Within 24 hours postoperatively;Time to first ambulationTimepoint: Within 24 hours postoperatively;Quadriceps muscle strengthTimepoint: At 24 hours postoperatively;Block related complications including vascular puncture hematoma and local anesthetic toxicityTimepoint: Intraoperative and within 24 hours postoperatively | — |
Countries
India
Contacts
Department Of Anaesthesiology And Critical Care Command Hospital Western Command Chandimandir