Health Condition 1: Z419- Encounter for procedure for purposes other than remedying health state, unspecified
Conditions
Interventions
Intervention1: Dexmedetomidine: Dexmedetomidine will be administered intravenously as a loading dose followed by continuous infusion for sedation during awake fiberoptic intubation as per the approved
Sponsors
Dr. Mouli Pundir
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged eighteen to seventy years belonging to American Society of Anesthesiologists physical status class One to Three, scheduled for surgery under general anesthesia with anticipated difficult airway and planned awake fiberoptic intubation, who are willing to participate and provide informed consent.
Exclusion criteria
Exclusion criteria: Pregnant patients, patients with history of chronic opioid use, patients receiving alpha two adrenoceptor agonists or antagonists within the previous fourteen days, patients with history of unstable angina or myocardial infarction, patients with bradycardia or heart block, and patients refusing to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation success score during awake fiberoptic intubationTimepoint: Intubation success score during awake fiberoptic intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters including heart rate blood pressure and oxygen saturationTimepoint: Baseline and every two minutes until completion of intubation;Time required for intubationTimepoint: From insertion of fiberoptic bronchoscope to confirmation of tracheal intubation;Number of intubation attempts Timepoint: During awake fiberoptic intubation;Tolerance of endotracheal tubeTimepoint: Immediately after successful intubation;Ramsay sedation scale scoreTimepoint: Baseline ten minutes after start of drug infusion and during airway anesthesia;Incidence of hypoxemia cough episodes and recall of procedureTimepoint: During intubation and at twenty four hour postoperative follow up | — |
Countries
India
Contacts
Public ContactDr Mouli Pundir
Shri Guru Ram Rai Institute of Medical And Health Sciences
Outcome results
None listed