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A study in patients with Parkinson s disease undergoing Deep Brain Stimulation Surgery to see how dexmedetomidine affects brain signal recordings

A Comparative Study of the effects of Dexmedetomidine versus no sedation on Microelectrode recording signals during Deep Brain Stimulation Surgery. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107960
Enrollment
32
Registered
2026-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Conscious sedation: Effects on microelectrode recording signals during deep brain stimulation surgery Control Intervention1: Dexmedetomidine: Effects of Dexmedetomidine on microelectrod

Sponsors

Institute of Neurosciences Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Idiopathic Parkinsons disease scheduled for bilateral STN DBS ASA physical status II and III

Exclusion criteria

Exclusion criteria: Contraindications to awake craniotomy Allergy to Dexmedetomidine. Significant cardiac disease Significant hepatic impairment. Inability to give informed consent. Any pain in either of the two groups Conversion to General anesthesia

Design outcomes

Primary

MeasureTime frame
Mean firing rate Interspike Interval Timepoint: Entry of electrode in STN—

Secondary

MeasureTime frame
mean arterial pressure heart rate perioperative complications overall cooperation with neurophysiologist during clinical testingTimepoint: Baseline 5 minutes 10 minutes 15 minutes 20 minutes 25 minutes 30 minutes—

Countries

India

Contacts

Public ContactIsra Hasnain

Institute of Neurosciences Kolkata

bibhukalyanidas@gmail.com9836000519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026