None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 50 65 years who have experienced amenorrhea for at least 12 months, confirmed by blood tests showing low estrogen levels. 2. Pre-sarcopenia or risk of sarcopenia based on AWGS 2019 criteria (low muscle mass or strength without severe mobility loss) having a score of SARC-CalF more than or equal to 11. 3. Ambulatory, able to walk independently without assistive devices 4. Stable medical condition and not on anti-inflammatory or hormonal therapy in the past 6 months 5. Willing to provide informed consent and comply with intervention and follow-ups
Exclusion criteria
Exclusion criteria: 1- severe cardiopulmonary, renal, hepatic or neurological disorders affecting exercise participation 2- recent fractures or orthopedic surgery or severe arthritis limiting mobility 3- current hormone replacement therapy or long term corticosteroid use 4- active malignancy, autoimmune, or chronic inflammatory disease. 5-uncontrolled diabetes or hypertension. 6- participation in regular resistance training. 7- cognitive impairement or psychiatric illness limiting compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biomarkers- IL6 & CRP Muscle Strength- Handheld dynamometer Fatigue- Fatigue severity scale Functional outcomes- ICF Timepoint: Pre- baseline, Interim- 3 weeks and Post intervention at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Peak expiratory flow rateTimepoint: Pre- baseline, Interim- 3 weeks & Post intervention at 3 months | — |
Countries
India
Contacts
Bharati vidyapeeth school of physiotherapy