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Assessment of Healing of Lesion Around Tooth Root After Root Canal Treatment Using Three Different Cleaning Methods

Clinical and Radiographic Assessment of Periapical Healing following root canal treatment using Three Different Irrigation Protocols along with Bioceramic sealer: A Randomised Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107918
Enrollment
54
Registered
2026-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Ultrasonic activated irrigation: After completion of biomechanical preparation, the root canal will be dried with sterile paper points and irrigated with 2 ml of 3% sodium hypochlorite.

Sponsors

Dr Pratiksha Mukundrao Munde
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Single-rooted permanent teeth indicated for primary root canal treatment 2.Teeth diagnosed with pulpal necrosis with asymptomatic apical periodontitis. 3.Presence of periapical lesion evident on radiographic examination, according to CBCT PAI score 3 5 introduced by Estrela et al. 4.Teeth with mature apices 5.Patients with good oral hygiene maintenance 6.Patients willing to participate in the study and comply with the follow-up schedule 7.Patients providing written informed consent

Exclusion criteria

Exclusion criteria: 1.Teeth with a history of previous root canal treatment 2.Teeth with open apices, internal or external root resorption 3.Teeth with root fractures or cracks 4.Teeth associated with advanced periodontal disease 5.Teeth with calcified canals or complex root canal anatomy 6.Patients with systemic diseases known to affect bone or soft tissue healing 7.Patients on long-term antibiotic, steroid, or immunosuppressive therapy 8.Pregnant or lactating women 9.Patient with any allergic tendencies pertaining to treatment. 10.Deleterious habits. E.g. Smoking, alcohol consumption etc.

Design outcomes

Primary

MeasureTime frame
Periapical healing and clinical parameters will be assessed.Timepoint: 3 months, 6 months, 9 months and 1 year

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Nitin Manoharrao Lokhande

SMBT Dental College and Hospital, Sangamner

drnlokhande@gmail.com7709387538

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026