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To study spread of colorectal cancer

To study lymph nodal yield and pattern of spread in non formalin fixed freshly resected surgical specimen in colorectal cancer an open labelled randomized controlled trial - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107895
Enrollment
80
Registered
2026-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C182- Malignant neoplasm of ascending colon Health Condition 2: C183- Malignant neoplasm of hepatic flexure Health Condition 3: C184- Malignant neoplasm of transverse colon Health Condition 4: C185- Malignant neoplasm of splenic flexure Health Condition 5: C186- Malignant neoplasm of descending colon Health Condition 6: C187- Malignant neoplasm of sigmoid colon Health Condition 7: C188- Malignant neoplasm of overlappingsites of colon Health Condition 8: C189- Malignant neopla

Interventions

Intervention1: lymph node dissection in freshly resected colorectal specimens: lymph node dissection in freshly resected colorectal specimens in operating room based on distance from the primary tumor

Sponsors

Post Graduate Institute Of Medical Education And Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with evidence of biopsy proven non metastatic colon cancer scheduled for elective surgery both open and laparoscopic 2.Patients with evidence of biopsy proven non metastatic rectal cancer after NACRT or Upfront rectal cancer resection scheduled for elective surgery both open and laparoscopic 3.Patients with probable diagnosis of colon and rectal cancer scheduled for emergency surgery who undergo complete oncological resection 4.between 14 and 85 years 5.Both sexes 6.Patients who give valid informed consent

Exclusion criteria

Exclusion criteria: 1.Patients in emergency who do not undergo complete oncological resections 2.Patients with proven metastasis in colorectal cancer 3.Age less than 14 years and more than 85 years 4.Patients unwilling to participate in the study due to any reason

Design outcomes

Primary

MeasureTime frame
lymph node yield in non-formalin fixed freshly resected surgical specimen in colorectal cancerTimepoint: baseline in operating room and After final histopathology report

Secondary

MeasureTime frame
1.Pattern of lymph nodal yield including positive lymph nodes & total lymph node yield based on distance from tumor in non formalin fixed freshly resected surgical specimen in colorectal cancer 2.Correlation between lymph node yield with other tumor & clinical characteristics Timepoint: baseline in operating room & after final histopathology report

Countries

India

Contacts

Public ContactSatish SN

Post Graduate Institute OF Medical Education And Research Chandigarh

drsnsatish06@gmail.com9790674694

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026