Use of growth factor fibers for gum disease treatment without surgery

CLINICAL EVALUATION OF EFFICACY OF INSULIN-LIKE GROWTH FACTOR (IGF) FIBRES AS LOCAL DRUG DELIVERY AGENT IN NON-SURGICAL MANAGEMENT OF CHRONIC PERIODONTITIS: A SPLIT-MOUTH CLINICAL STUDY - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107871

Enrollment

Registered

2026-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Group B(test group): Scaling and root planing along with IGF(Insulin-like growth factor) as local drug delivery: A written informed consent will be taken from all the patients included

Eligibility

Inclusion criteria

Inclusion criteria: Age 20-55 years Male and female patients with chronic periodontitis Presence of at least two contralateral sites with probing pocket depth (PPD) of 5-6 mm Systemically healthy patients

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Smokers and tobacco users Hypertension Diabetes Any other systemic disorders which affect the outcome of the treatment. Patients who are unwilling to participate in the study. Patients with chronic periodontitis showing radiographic evidence of angular bone defects.

Design outcomes

Primary

Measure	Time frame
REDUCTION IN PROBING POCKET DEPTHTimepoint: Baseline,3months	—

Secondary

Measure	Time frame
REDUCTION IN PLAGUE INDEX REDUCTION IN GINGIVAL INDEX GAIN IN CLINICAL ATTACHMENT LEVELTimepoint: BASELINE AND 3MONTHS	—

Countries

India

Contacts

Public ContactDr JAMES SAMUEL

Goa Dental College and Hospital, Goa

jamessamueldental@gmail.com9822151608

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026