Health Condition 1: Q821- Xeroderma pigmentosum
Conditions
Interventions
Intervention1: Application of 5 percent imiquimod cream: 5 percent imiquimod cream to be applied on affected areas 5 times a week for 16 weeks followed by twice per week for next 8 weeks.
Control Inte
Sponsors
Dr Neetu Bhari
Eligibility
Inclusion criteria
Inclusion criteria: Patients with a clinical diagnosis of xeroderma pigmentosum more than 8 years of age, with at least a clinically and/or histopathologically confirmed premalignant or/and low-risk malignant skin lesion (histologically low-grade subtypes).
Exclusion criteria
Exclusion criteria: 1. Patients with clinical diagnosis of Xeroderma pigmentosum presenting with only mild pigmentary dyschromia. 2. Xeroderma pigmentosum patients less than 8 years of age. 3. Patients with significant neurological or systemic involvement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in premalignant and/or malignant skin lesions in Xeroderma Pigmentosum patients at the end of 6 months of application of 5 percent imiquimod cream.Timepoint: Improvement in premalignant and/or malignant skin lesions in Xeroderma Pigmentosum patients at the end of 6 months of application of 5 percent imiquimod cream. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in pigmentary dyschromia in Xeroderma Pigmentosum patients.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactGadegone Savi Ulhasrao
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed