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Study to assess the prognostic significance of presepsin in hospital-acquired and ventilator-associated pneumonia

Study to Assess the Prognostic Significance of Presepsin in Hospital Acquired and Ventilator Associated Pneumonia A Prospective Cohort Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/107850
Enrollment
81
Registered
2026-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection Health Condition 2: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Saby anna kunjumon
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Blood samples for presepsin and procalcitonin were drawn within 24 hours of each other from the time of confirmation or within 24 hours of HAP or VAP

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Severe chronic conditions like terminal cancer and acquired immunodeficiency syndrome might confound the results or influence mortality independently of sepsis Mortality occurring after the follow-up period of 30 days Patients or legal representatives who refuse to participate in the study

Design outcomes

Primary

MeasureTime frame
ROC Curve Analysis for predicting 30-day mortality in HAP and VAP patientsTimepoint: from 2nd may 2025 to 2nd november 2026

Secondary

MeasureTime frame
ROC Curve Analysis for evaluating the performance of presepsin and PCT in predicting septic shock in HAP and VAP patients.Timepoint: from 2nd may 2025 to 2nd november 2026;Correlation between presepsin and PCT levels versus PSI score, SOFA score, Ventilator free days, and ICU stay duration. - Pearson correlation for normally distributed data - Spearman correlation for non-normally distributed data Timepoint: from 2nd may 2025 to 2nd november 2026

Countries

India

Contacts

Public ContactSaby anna kunjumon

AIIMS rishikesh

drprakhar2009@gmail.com8979616104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026