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Comparison of a natural bee product (propolis) mouth rinse and chlorhexidine mouth rinse for improving gum health and lowering bacteria after full-mouth deep cleaning in people with moderate gum disease.

Comparative evaluation of clinical outcomes and microbial load after one-stage full mouth disinfection with 20% propolis hydroalcoholic rinse and 0.2% chlorhexidine rinse in stage II grade B periodontitis patients: a single-blind randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107841
Enrollment
40
Registered
2026-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: One-stage full-mouth disinfection with 20 percent propolis hydroalcoholic rinse: Subjects will receive one-stage full-mouth disinfection using 20% propolis hydroalcoholic rinse in a sin

Sponsors

sanskruti kulkarni
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants maintaining good oral hygiene after completion of scaling and root planing. Patients diagnosed with stage II grade B periodontitis three or more nonadjacent teeth with pockets more than or equal to 5 mm

Exclusion criteria

Exclusion criteria: Patients with chronic diseases such as diabetes mellitus, arthritis, thyroid disorder, etc. Patients who are smokers or using any other tobacco products. Patients who had undergone subgingival instrumentation within 12 months before the baseline examination. Patients with compromised medical conditions which required prophylactic antibiotic coverage Patients who had used antimicrobial agents 4 months before the study

Design outcomes

Primary

MeasureTime frame
Change in clinical periodontal parameters, including Gingival Index (GI), Plaque Index (PI), Modified Sulcus Bleeding Index (MSBI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL), following one-stage full mouth disinfection using 20% propolis hydroalcoholic rinse and 0.2% chlorhexidine rinse in Stage II Grade B periodontitis patients.Timepoint: Change in clinical periodontal parameters, including Gingival Index (GI), Plaque Index (PI), Modified Sulcus Bleeding Index (MSBI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL), following one-stage full mouth disinfection using 20% propolis hydroalcoholic rinse and 0.2% chlorhexidine rinse in Stage II Grade B periodontitis patients at 24 hours and 12 weeks—

Secondary

MeasureTime frame
Change in microbial load assessed by colony forming units (CFUs) following one-stage full mouth disinfection using 20% propolis hydroalcoholic rinse and 0.2% chlorhexidine rinse in Stage II Grade B periodontitis patients.Timepoint: baseline, 24 hours, 12 weeks—

Countries

India

Contacts

Public Contactsanskruti kulkarni

MGVS KBH dental college and hospital,panchvati,nashik

trivenikale@yahoo.com8552011711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026