Skip to content

A study to see whether treating severe gum disease can help lower blood pressure, reduce inflammation, and improve cholesterol levels in people who already have high blood pressure

EFFECT OF PERIODONTAL THERAPY ON BLOOD PRESSURE LEVELS,SERUM C-REACTIVE PROTEIN AND LIPID PROFILE IN HYPERTENSIVE PATIENTS WITH STAGE III PERIODONTITIS-A CLINICO HEMATOLOGICAL STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107822
Enrollment
35
Registered
2026-04-07
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: scaling and root planing followed by flap surgery: Scaling and root planing will be performed to eliminate subgingival plaque and calculus, thereby reducing periodontal inflammation. Pa

Sponsors

Dr SWATHI S MALAGATTI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of age more than 18 years 2) Patients with known hypertension 3) Patients with stage III Periodontitis (probing depth greater than or equal to 6mm) 4) Patients with radiographic evidence of bone loss

Exclusion criteria

Exclusion criteria: (1) active infectious diseases, such as hepatitis, HIV, or tuberculosis, (2) pregnant or breastfeeding, and (3) taking nonsteroidal anti-inflammatory drugs on a regular basis or taking antibiotics within 3 months of assessment. (4) Smokers

Design outcomes

Primary

MeasureTime frame
1)To evaluate the efficacy of non surgical periodontal therapy(scaling and root planing) and surgical therapy on clinical parameters,blood pressure,serum crp and lipid profile in hypertensive patients with stageIII periodontitis. 2) 3)To compare the effect of surgical and non surgical periodontal treatment on clinical parameters,blood pressure,serum crp and lipid profile in hypertensive patients with Stage III periodontitis.Timepoint: assessed at baseline,2 weeks and 3 months

Secondary

MeasureTime frame
1) To evaluate the efficacy of non surgical periodontal therapy(scaling and root planing) on clinical parameters,blood pressure,serum crp and lipid profile in hypertensive patients with stageIII periodontitis. 2) To evaluate the efficacy of surgical therapy on clinical parameters,blood pressure,serum crp and lipid profile in hypertensive patients with Stage III periodontitis. 3) To compare the effect of surgical and non surgical periodontal treatment on clinical parameters,blood pressure,serum crp and lipid profile in hypertensive patients with Stage III periodontitis. Timepoint: At the baseline a detailed case history, clinical parameters which includes plaque index (PI), Gingival Index (GI), Bleeding on probing (BOP), clinical attachment loss (CAL) and Probing pocket depth (PPD) will be recorded and blood samples will be collected for detection of c reactive protein levels and lipid profile and blood pressure to be recorded.The same is followed at 2 weeks after SRP and 3 months after flap surgery

Countries

India

Contacts

Public ContactDrSwathi S Malagatti

COORG INSTITUTE OF DENTAL SCIENCES

amitakw@rediffmail.com9480085687

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026