Testing krishnatiladi and siddharthakadi pastes for treating dark facial spots(melasma)

RANDOMISED COMPARATIVE STUDY TO EVALUATE THE EFFECT OF KRISHNATILADI LEPA AND SIDDHARTHAKADI LEPA IN MANAGEMENT OF VYANGA W.S.R. TO MELASMA - KSV Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107739

Enrollment

Registered

2026-04-07

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 50 years Patients irrespective of sex religion occupation Chronicity less than 5 years Patients with classical signs and symptoms of Vyanga Roga

Exclusion criteria

Exclusion criteria: Patients having age below 18 years and above 50 years With present history of chronic diseases of skin like Psoriasis Vitiligo Dermatitis etc Patients known case of genetic skin disorder sensitive skin Individuals presenting with hyperpigmentation due to systemic disorders such as Addisons disease or Cushings syndrome congenital conditions like Navus of Ota or neoplastic causes including malignant melanoma etc

Design outcomes

Primary

Measure	Time frame
To evaluate the comparative effect of Krishnatiladi Lepa and Siddharthakadi Lepa in the management of Vyanga W.S.R. to MelasmaTimepoint: 45 days	—

Secondary

Measure	Time frame
To explore the physiological understanding of Twak Sharir in the context of Vyanga, and correlate it with the modern pathophysiology of melasma. To assess improvements in dermatological parameters such as pigmentation intensity, patch size, and skin tone using both Ayurvedic and modern evaluation methods before and after the intervention. To determine the safety, acceptability, and tolerability of the Lepa formulations i n long- term use. To compare the physiological impact of Krishnatiladi and Siddharthakadi Lepa o n Vyanga MelasmaTimepoint: 45 days	—

Measure

Time frame

To explore the physiological understanding of Twak Sharir in the context of Vyanga, and correlate it with the modern pathophysiology of melasma. To assess improvements in dermatological parameters such as pigmentation intensity, patch size, and skin tone using both Ayurvedic and modern evaluation methods before and after the intervention. To determine the safety, acceptability, and tolerability of the Lepa formulations i n long- term use. To compare the physiological impact of Krishnatiladi and Siddharthakadi Lepa o n Vyanga MelasmaTimepoint: 45 days

—

Countries

India

Contacts

Public ContactDr Ankita

Madan Mohan Malviya Government Ayurved College

drankitarvind.1990@gmail.com9461058087

Outcome results