Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A will receive sugammadex as reversal agent: Group A participants will receive 2mg/kg of Sugammadex IV when spontaneous recovery had reached a second twitch after TOF, or 4 mg/Kg
Sponsors
All India institute of medical sciences- Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age: more than or equal to 50 years 2.ASA class I or II or III 2. All patients undergoing diagnostic or therapeutic bronchoscopy 3.Patients giving consent for procedure.
Exclusion criteria
Exclusion criteria: 1.Patient already underwent any thoracic surgery in the past. 2.Patient with ventilated support 3.severe cardiac diseases (EF less than 30%) 4.History of allergy to any reversal drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| extubation time in the older adult patient under going bronchoscopyTimepoint: At the time of extubation of trachea | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare intraoperative and post operative vitals (heart rate, Spo2, BP) related to use of Sugammadex vs Neostigmine 2.to compare the post operative residual paralysis/pulmonary function after reversal from neuromuscular blockade by Sugammadex vs Neostigmine based on breath holding time after 60 minutes of extubation . 3.Compare any complications associated with use of Sugammadex vs Neostigmine like hypotension, bronchospasm, apnea, pneumonia, atelectasis etc. Timepoint: During intraoperative period and 1 hour of post extubation in PACU | — |
Countries
India
Contacts
Public ContactDr Mridul Dhar
All India institute of medical sciences- Rishikesh
Outcome results
None listed