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Comparing Two Neck Spine Operations in Patients with Spinal Cord Pressure: Is Nerve Monitoring Helpful?

A Randomized Controlled Trial Comparing Cervical Laminectomy with and without Intraoperative Neuromonitoring in Degenerative Cervical Myelopathy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107688
Enrollment
100
Registered
2026-04-07
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M471- Other spondylosis with myelopathy Health Condition 2: M480- Spinal stenosis

Interventions

Intervention1: Posterior cervical enbloc laminectomy and instrumentation: Posterior cervical decompression will be performed by enbloc laminectomy at the clinically and radiologically involved levels.

Sponsors

Ganga Orthopaedics Research and Education Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients more than 18 years of age, Clinical diagnosis of cervical myelopathy, Multilevel involvement - more than 2 levels requiring posterior decompression, Neuutral or lordotic cervical spine, Ability to provide written informed consent

Exclusion criteria

Exclusion criteria: -cervical kyphosis -Conditions requiring anterior and posterior surgery -Previous cervical spine surgery - Trauma, infection, tumor, or inflammatory spinal disease

Design outcomes

Primary

MeasureTime frame
To compare the intraoperative neuromonitoring responses, specifically motor-evoked potentials (MEPs) and somatosensory-evoked potentials (SEPs), between en bloc and piecemeal laminectomy techniques in patients undergoing surgery for cervical spondylotic myelopathy, with respect to the incidence of signal improvement, deterioration, or no change during decompression.Timepoint: preop, immediate postop, 24 hours, 48 hours, 72 hours, 3 months, 6 months, 1 year—

Secondary

MeasureTime frame
3.2.Secondary objectives (if any): To compare the incidence of intraoperative and postoperative neurological complications, including transient or persistent neurological worsening, between the two groups. To assess and compare clinical neurological outcomes using the modified Japanese Orthopaedic Association (mJOA) score at follow-up. To compare the incidence of dural tear and postoperative cerebrospinal fluid leakage, operating time, and blood loss between en bloc and piecemeal laminectomy techniques. To analyze the relationship between intraoperative neuromonitoring changes and postoperative neurological recovery in patients undergoing posterior cervical decompression.Timepoint: preop, immediate postop, 24 hours, 48 hours, 72 hours, 3 months, 6 months, 1 year—

Countries

India

Contacts

Public ContactProf SRajasekaran

Ganga Medical Centre and Hospital

rajasekaran.orth@gmail.com9843022325

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026