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A comparison between using granisetron with dexamethasone and ondansetron with dexamethasone to prevent nausea and vomiting after surgery in adults having planned laparoscopic operations

Comparison Of Granisetron Dexamethasone Combination And Ondansetron Dexamethasone Combination As Prophylaxis For Postoperative Nausea And Vomiting In Adults Undergoing Elective Laparoscopic Surgery - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107685
Enrollment
100
Registered
2026-04-07
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K352- Acute appendicitis with generalized peritonitis Health Condition 2: K501- Crohns disease of large intestine Health Condition 3: K929- Disease of digestive system, unspecified Health Condition 4: K200- Eosinophilic esophagitis Health Condition 5: K638- Other specified diseases of intestine Health Condition 6: K510- Ulcerative (chronic) pancolitis Health Condition 7: K910- Vomiting following gastrointestinal surgery Health Condition 8: K910- Vomiting following gastrointes

Interventions

Intervention1: Nil: Nil Intervention2: General Anaesthesia: to intubate patient undergoing laparoscopic surgeries Control Intervention1: Inj Granisetron (2mg), Inj Ondansetron (4mg), Inj Dexamethasone

Sponsors

PACIFIC MEDICAL AND MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthiologists(ASA) physical status 1/2 Planned for elective laparoscopic surgery under general anaesthesia Patients undergoing elective lower abdominal surgeries under general anaesthesia BMI-20 and 30 kg/m2

Exclusion criteria

Exclusion criteria: Patients who refused to give consent. Patients who had received opioids non-steroidal anti-inflammatory drugs,steroids,and antiemetic agents during previous 24 hour Patients with history of PONV severe cardiorespiratory,hepatic,renal,neurological,or endocrinologist disease,pregnant and lactating women,obesity,diabetes mellitus

Design outcomes

Primary

MeasureTime frame
Granisetron Dexamethasone combination for postoperative nausea and vomiting is prolongedTimepoint: 1 day—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Tasha Purohit

Pacific Medical College And Hospital

tashapurohit@gmail.com9587850617

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026