Health Condition 1: 1- Obstetrics
Conditions
Interventions
Intervention1: Nebulised Dexmedetomidine: 1 mcg/kg in 4 ml 0.9 % normal saline nebulization 12 hourly
Control Intervention1: Nebulised Fentanyl: 1 mcg/kg in 4 ml 0.9 % normal saline nebulization 12 ho
Sponsors
KPC Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients belonging to ASA Grade II and III Patients giving informed written valid consent. Subjects that qualified the PDPH criteria as per International Headache Society with headache severity scores of greater than 4
Exclusion criteria
Exclusion criteria: Age less than 18 years and more than 35 years Known allergy to the anesthetic agents involved in the study Known case of cardiovascular disorders, specifically bradyarrhythmias. Patients with chronic treatment of headache of other causes, history of migraine, history of epilepsy, history of substance abuse and current opioid use. Patients who are uncooperative or disoriented. Parturients with Body mass index greater than 25 kg/m2 Known cases of gestational hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache severity as measured using Numeric Pain Rating Scale (NPRS) after 24 hours of the first nebulisation using Dexmedetomidine versus FentanylTimepoint: At baseline,1,6,12,24,48 and 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the duration of PDPH while using 12 hourly nebulization of dexmedetomidine versus fentanyl. Timepoint: At baseline,1,6,12,24,48 & 72 hours;To compare the hemodynamics after 24 hours of nebulization using dexmedetomidine versus fentanylTimepoint: At baseline,1,6,12,24,48 & 72 hours | — |
Countries
India
Contacts
Public ContactSpandan Paul
KPC Medical College and Hospital
Outcome results
None listed