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A STUDY COMPARING ANAESTHESIA WITHOUT OPIOID AND WITH OPIOIDS IN PATIENTS UNDERGOING THYROID AND PARATHYROID SURGERY

COMPARISON OF OPIOID-FREE AND OPIOID- INCLUSIVE PROPOFOL ANAESTHESIA FOR THYROID AND PARATHYROID SURGERY: A RANDOMISED CONTROLLED TRIAL - NO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107626
Enrollment
52
Registered
2026-04-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E049- Nontoxic goiter, unspecified

Interventions

Intervention1: Opioid free anaesthesia: Propofol based general anaesthesia without the use of opioids to reduce the incidence of PONV.Anaesthesia will be maintained using propofol along with non-opioi
plexus block for analgesia Control Intervention1: Opioid inclusive anaesthesia: Fentanyl is a potent mu receptor agonist used in opioid-inclusive anaesthesia consisting of propofol-based general anaes

Sponsors

Institute of Anaesthesiology Government Rajaji Hospital and Madurai Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I-III, undergoing elective thyroid and parathyroid surgery

Exclusion criteria

Exclusion criteria: Patients with airway compression, cardiac, liver and renal disease, pregnancy or lactation, giant thyroid surgery, coagulation disorders, allergy to study drugs

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative nausea and vomitingTimepoint: Within 48 hours postoperatively—

Secondary

MeasureTime frame
Intraoperative hemodynamic parameters, postoperative pain scores, rescue analgesic requirementTimepoint: Intraoperative period and up to 48 hours postoperatively—

Countries

India

Contacts

Public ContactDr Padma Priya C R

Institute of Anaesthesiology Government Rajaji Hospital and Madurai Medical College

drvairav@yahoo.co.in9842100336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026