Comparison of two drugs (Dexmedetomidine and Fentanyl) added to local anaesthesia for pain relief in shoulder surgeries

To compare the effect of dexmeditomedine and fentanyl as an adjuvant to bupivacaine in peripheral nerve stimulator guided interscalene brachial plexus block in shoulder surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107592

Enrollment

Registered

2026-04-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S422- Fracture of upper end of humerus Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmeditomedine: Dexmeditomedine ia a highly selective alpha2 adrenergic receptor agonist having 8 times more affinity compared to alpha1, it is used as an adjuvant to local aesthetic a

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 and 2 Patient undergoing elective shoulder surgeries Duration of surgery 120-180 minutes

Exclusion criteria

Exclusion criteria: Patient refusal Allergy to local anaesthetic and opioids Local infection at the site of block Pregnant women Severe cardiopulmonary disease Patient with neurological deficit in operating arm

Design outcomes

Primary

Measure	Time frame
to compare the effect of dexmeditomidine and fentanyl used as an adjuvant to bupivacaine in post operative analgesia given as inter scalene brachial plexus block in shoulder surgeriesTimepoint: 6 hours	—

Secondary

Measure	Time frame
time of onset of secondary blockade duration of secondary blockade time of onset of motor blockade duration of onset of motor blockade incidence of side effectsTimepoint: 6 hours	—

Countries

India

Contacts

Public ContactKaruna Taksande

Dutta Meghe Institute of Medical Sciences and Research

karunahp1878@gmail.com7722037738

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026