A clinical study to assess how effective Nirgundi Rectal Suppositories are in managing Pain after Hemorrhoidectomy surgery.

An Open label Randomized controlled clinical study to evaluate the efficacy of Nirgundi Rectal Suppository in the Management of Post-Operative Pain in Haemorrhoidectomy - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107551

Enrollment

Registered

2026-04-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K649- Unspecified hemorrhoids

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of age group between 21-65 years, either of gender, caste, religion, occupation. 2) Patients who underwent elective Haemorrhoidectomy either Open (MilliganMorgan)and Closed (Ferguson) under spinal anaesthesia. 3) Patients willing to provide written informed consent and follow up the protocol of study will be selected. 4) 1-2 internal haemorrhoids. 5) 1 externo internal haemorrhoid.

Exclusion criteria

Exclusion criteria: 1) Positive reaction to Diclofenac sensitivity test (intradermal) conducted prior to enrolment. 2) Patients who are pregnant or lactating. 3) Participants with a prior history of anorectal surgical interventions or existing comorbid ano rectal conditions. 4) Patients who are operated for haemorrhoids associated with IBS or diagnosed with Crohn s Disease, Ulcerative Colitis. 5) Patients with known allergies or hypersensitivity to Diclofenac. 6) Immune compromised patients. 7) Patients diagnosed with systemic diseases like Tuberculosis, Rheumatoid Arthritis, Ischemic Heart Disease, portal hypertension, Type 2 Diabetes Mellitus, Hypertension. 8) History of Human Immunodeficiency Virus (HIV), HBsAg infection, and Venereal Diseases. 9) Post-operative Anaesthesia Complications. 10) Post-operative Fulminating Infections. 11) Individuals with known history of Chronic Alcoholism. 12)Individuals with a known history of Coagulopathy.

Design outcomes

Primary

Measure	Time frame
Progressive relief from pain due to surgical intervention at operative siteTimepoint: Assessment on every 2 hours of 1st post operative day (1 Day) for gradual relief of pain according to VAS scale	—

Secondary

Measure	Time frame
To improve the quality of life. -Generation of in-depth analyzed data on different aspect of the disease.Timepoint: 1 Day	—

Countries

India

Contacts

Public ContactDr Geetanjali Hiremath

Shree Jagadguru Gavisiddeshwara Ayurvedic Medical College and Hospital Koppal

sanjalihiremath@gmail.com7760346752

Outcome results