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Study on the relationship between ventilator pressure measures in critically ill adults participants on the ventilator and the effect of these measures on outcomes such as duration of stay in the intensive care unit and number of days without the need of ventilator support.

Dynamic mechanical power and dynamic driving pressure: correlation and clinical outcomes in mechanically ventilated critically ill adults - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/107550
Enrollment
85
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J969- Respiratory failure, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

Nisha Lilly Ninan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults, more than or equal to 18 years of age, intubated in hospital, with expected mechanical ventilation duration more than 72 hours and first intubation this admission

Exclusion criteria

Exclusion criteria: Extracorporeal membrane oxygenation at any time during the period of the study; severe air leaks or chest tubes with ongoing leak; high frequency oscillation; moribund or comfort-care; pregnant patients; patients intubated in another hospital for more than 72 hours within one month of the present admission

Design outcomes

Primary

MeasureTime frame
To determine the correlation between dynamic mechanical power and dynamic driving pressure in adult critically ill mechanically ventilated patientsTimepoint: Every 4 hours for the first 72 hours of mechanical ventilation

Secondary

MeasureTime frame
To evaluate the impacts of peak dynamic mechanical power & peak dynamic driving pressure, number of episodes where dynamic mechanical power exceeds 15 joules per minute & where dynamic driving pressure exceeds 15 centimeters of water, & the median dynamic mechanical power & the median dynamic driving pressure per patient over the first 72 hours, on intensive care unit length of stay & ventilator free days at 28 daysTimepoint: First 72 hours on mechanical ventilation

Countries

India

Contacts

Public ContactBabu K Abraham

Apollo Hospitals, Chennai

abrahambk@gmail.com9884286660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026