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Study compare inflammatory markers calculated from routine blood tests are different in patients of psoriasis compared to normal healthy individuals and how it is related to severity of psoriasis in the patients

Systemic immune-inflammation index (SII) and Systemic Inflammation Response Index (SIRI): Evaluation of alteration in novel complete blood count-derived biomarkers and their association with disease severity in psoriasis - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/107537
Enrollment
120
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L409- Psoriasis, unspecified

Interventions

Intervention1: Nil: Nil

Sponsors

Department of Dermatology, Sri Guru Ram Das Institute of Medical Sciences and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 70 years with clinically diagnosed chronic plaque psoriasis who are willing to give informed consent Healthy controls of similar age and sex

Exclusion criteria

Exclusion criteria: Patients with other autoimmune diseases Patients with active infections or malignancy Patients on antiplatelet or anticoagulant drugs Patients on systemic immunomodulatory therapy in last 2 months Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
Difference in Systemic Immune-Inflammation Index (SII) and Systemic Inflammation Response Index (SIRI) between psoriasis patients and healthy controls.Timepoint: At baseline (time of enrollment)—

Secondary

MeasureTime frame
Correlation of SII and SIRI with disease severity assessed by PASI.Timepoint: At baseline—

Countries

India

Contacts

Public ContactTony Sam James

Sri Guru Ram Das Institute of Medical Sciences and Research

drsaurabhsharma@yahoo.co.in9815162491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026