Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Surgical plethysmographic index guided analgesia: Intraoperative remifentanil infusion titrated according to Surgical plethysmographic index monitoring to maintain SPI within target ran
Sponsors
Sir Ganga Ram Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Both males and females, aged 18-65 years ASA physical classification I to II
Exclusion criteria
Exclusion criteria: Known uncontrolled cardiovascular disease (e.g., hypertension, systolic and diastolic dysfunction) Liver function abnormality (liver enzymes more than 2 times the normal range) Kidney function abnormality (serum creatinine more than 1.4 mg/dl) Known psychiatric or neurological disorder Known uncontrolled endocrine disorder (diabetes mellitus, hypothyroidism) Known allergy or hypersensitivity to the study drug Recent intake of sedative medication or anti-psychotic medication Substance abuse Anticipated need for postoperative ventilation Refusal to informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Remifentanil ConsumptionTimepoint: from induction of anaesthesia to competion of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Postoperative pain (10-point NRS) during the first 24-hrs postoperative period 2. Postoperative nausea and vomiting (3-point PONV score) during the first 24-hrs postoperative period 3. Intraoperative haemodynamic instability (bradycardia/ tachycardia/ hypotension/ hypertension) Timepoint: immediately after shifting to recovery, 6 hours and 24 hours after recovery | — |
Countries
India
Contacts
Public ContactDr Srishti
Sir Ganga Ram Hospital
Outcome results
None listed