Can a medicated chewing gum helps in reducing gum disease better than regular chewing gums?

Effectiveness of Ethylenediaminetetraaceticacid (EDTA) and Methyl Sulfonyl Methane (MSM) - Enriched Xylitol in comparison to conventional Xylitol Chewing Gums on dental Plaque accumulation: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107523

Enrollment

Registered

2026-04-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ethylene diamine tetra acetic acid (EDTA), Methyl Sulfonyl Methane (MSM) and Xylitol containing chewing gum.: EDTA, MSM and Xylitol containing chewing gum in reducing plaque and gingivi

Eligibility

Inclusion criteria

Inclusion criteria: Subjects agreed to cooperate and willing to participate with consent. Subjects with Gingival Index more than 1.

Exclusion criteria

Exclusion criteria: Subjects using any mouthwash or xylitol chewing gum. Subjects with oral lesions. Pregnant or lactating mothers. Subjects with crowding, malocclusion or developmental anomalies. Subjects with habits like smoking and tobacco chewing. Subjects on any antibiotics.

Design outcomes

Primary

Measure	Time frame
Effectiveness of EDTA and MSM enriched xylitol chewing gum on plaque.Timepoint: 15 days	—

Secondary

Measure	Time frame
Side effects of EDTA and MSMTimepoint: 15 days	—

Countries

India

Contacts

Public ContactSoumya Snigdhya Das

Pacific Dental College and Hospital

kailashasawaudr@yahoo.com9829040314

Outcome results