Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
Intervention1: Myoinositol: Group 1(Intervention) Drug- Myoinositol Dose- 1 gm Route- Per oral Frequency- Twice daily Duration- For 24 weeks
Control Intervention1: Metformin: Group 2(Comparator) Drug-
Sponsors
Dr. Priya Kumari
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 18-40 years. 2. Diagnosed with PCOS as per Rotterdam criteria 3.Willing to participate and provide written informed consent. 4. Patients not planning to get pregnant in 6 months
Exclusion criteria
Exclusion criteria: 1. Women with diabetes mellitus, thyroid disorders, or hyperprolactinemia. 2. Use of hormonal therapy, insulin sensitizers, or ovulation-inducing drugs within the last 3 months 3. Patients seeking treatment for infertility 4. Known liver, renal, or cardiovascular disease. 5. Pregnant or lactating women. 6. Hypersensitivity or intolerance to study medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare changes in HOMA-IR score following treatment with myo-inositol and metformin at 12 Weeks Timepoint: 12 Weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the effects of both drugs on 1) changes in HOMA-IR score following treatment with myo-inositol and metformin at 24 Weeks 2) Lipid profile 3) Clinical profile (menstrual cycle, Acne, Hirsutism, BMI, Wrist circumference, Waist circumference) To compare tolerability and side effects Timepoint: 12 weeks and 24 weeks | — |
Countries
India
Contacts
Public ContactDr Sangam Jha
AIIMS Patna
Outcome results
None listed