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Effect of non surgical treatment of gum disease on blood inflammatory markers level in patients with type II diabetes a clinical trial

Effects of non surgical periodontal therapy on red cell distribution width to platelet count ratio RPR as an inflammatory marker in type II diabetic patients with periodontitis a clinial trail - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107512
Enrollment
22
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non- surgical periodontal therapy(scaling and root planing): All participants will undergo full-mouth scaling and root planing using ultrasonic and hand instruments under local anesthes

Sponsors

Dr Arundhathi P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with type II diabetes mellitus Patients diagnosed with stage III grade B periodontitis Patients aged 30 to 65 years of either gender Patients undergoing periodontal therapy Patients providing written informed consent for participation in the study

Exclusion criteria

Exclusion criteria: Patients diagnosed with stage I and stage II periodontitis Patients who have received periodontal therapy or professional oral prophylaxis in the past 6 months Patients on antibiotics, anti-inflammatory drugs, or immunosuppressive therapy in the past 3 months Pregnant or lactating women Patients with other systemic diseases (cardiovascular disease, renal disease) that may affect periodontal status or hematological parameter Patients with smoking or tobacco habit Patients with hematological disorders or blood dyscrasias affecting red cell or platelet indices

Design outcomes

Primary

MeasureTime frame
To assess changes in red cell distribution width to platelet count ratio 6 to 8 weeks after non surgical periodontal therapy and to corelate with the clinical periodontal parametersTimepoint: at baseline after 6 weeks

Secondary

MeasureTime frame
To assess clinical periodontal parameters at baseline To assess glycemic parameters at the baseline To evaluate red cell distribution width & platelet count ratio (RPR)at baseline Timepoint: at baseline after 6 weeks

Countries

India

Contacts

Public ContactDr M M Dayakar

KVG dental college and hospital

mmdayakar@yahoo.com9448167427

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026