HERBAL ALTERNATIVE IN THE MANAGEMENT OF ORAL WHITE LESION

Development of Pomegranate and Raspberry Fruit Extract In-situ gel in Comparison with Topical Vitamin A in the management of Oral Leukoplakia - A Clinical Trial - NIL

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107471

Enrollment

Registered

2026-04-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R978- Other abnormal tumor markers

Interventions

Intervention1: Pomegranate and Raspberry Fruit Extract In-situ gel: Pomegranate and Raspberry Fruit Extract In-situ gel - To apply topically over the affected mucosa twice daily for a period of 3 mont

Eligibility

Inclusion criteria

Inclusion criteria: Patients with mild to moderate epithelial dysplasia

Exclusion criteria

Exclusion criteria: Patients with severe epithelial dysplasia

Design outcomes

Primary

Measure	Time frame
Reduction in Size of the lesion - at baseline, 2 weeks, 4 weeks, 6 weeks and after 3 months. Pre and post treatment serum glutathione synthetase levelsTimepoint: Reduction in Size of the lesion at baseline, 2 weeks, 4 weeks, 6 weeks and after 3 months. Pre treatment and post treatment serum glutathione synthetase levels - baseline and 3 months	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactKishorwara R

Saveetha Dental College and Hospitals

madhumahalingam05@gmail.com09384576836

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026