Skip to content

EVALUATION OF EFFECT OF NAGAVALLI VARTH IN THE MANAGEMENT OF CHRONIC FISSURE-IN-ANO

AN OPEN LABEL RANDOMIZED CLINICAL STUDY TO COMPARE THE EFFICACY OF NAGAVALLI VARTH WITH DICLOFENAC SUPPOSITORY IN THE MANAGEMENT OF CHRONIC FISSURE-IN-ANO - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107453
Enrollment
30
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K928- Other specified diseases of the digestive system

Interventions

None listed

Sponsors

Dr Nadhi Suresh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed case of chronic fissure-in-ano duration greater than six weeks Parikarthika, sadaha, parikartana, anilasanga Age group: 21 to 70 years, both genders willing to participate Complaints of pain during defecation, bleeding per rectum, burning sensation, post-defecation Single posterior anterior fissure on clinical examination. Willing to give written informed consent. Willing to comply with the treatment protocol and follow-up visits.

Exclusion criteria

Exclusion criteria: Acute fissure-in-ano duration less than 6 weeks. Pregnant women Known allergy or hypersensitivity to any components of diclofenac Psychiatric illness or cognitive impairment Patients suffering from systemic diseases like hepatitis, tuberculosis, HIV Patient with associated anorectal disease like fistula in ano, hemorrhoids, polyp, abscess and malignancy.

Design outcomes

Primary

MeasureTime frame
Nagavalli Varthi will result in significant pain reduction and healing of chronic fissure-in-ano compared to Diclofenac suppository. Severe pain to moderate pain From moderate to mild pain Significant healing of ulcerTimepoint: 14 days

Secondary

MeasureTime frame
Improvement in physical and psychological health Timepoint: 14th day

Countries

India

Contacts

Public ContactDr Nadhi Suresh

SRI SRI COLLEGE OF AYURVEDIC SCIENCE HOSPITAL AND RESEARCH

ayurvedabhishak@gmail.com09108254765

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026