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A simple eye test to predict success of blood patch treatment in headache patients with intracranial hypotension

Correlation between Optic Nerve Sheath Diameter and clinical improvement after lumbar Epidural Blood Patch in case of Spontaneous Intracranial Hypotension. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107451
Enrollment
20
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G89-G99- Other disorders of the nervous system

Interventions

Intervention1: EPIDURAL BLOOD PATCH(EBP): Lumbar EBP will be delivered by team of anaesthetists, through a midline approach under aseptic condition at the lumbar spine region (L2 L5). 20 ml of autolog

Sponsors

Institute Of Neurosciences, KOlkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1 and 2 NOT RESPONDING TO CONSERVATIVE TREATMENT BMI less than 24 kg/metre square DIAGNOSED WITH SIH EITHER IN CT OR MRI

Exclusion criteria

Exclusion criteria: GCS less than 14 ASA Grade III/ IV Patients with previous history of surgeries involving Lumbar area e.g. 1. Scoliosis correction surgery 2. Spinal instrumentation surgery History of congestive heart failure/ valvular heart disease/significant coronary artery diseases / cardiac conduction block/ chronic kidney diseases/ hepatic disease/ pulmonary disease/ neuropsychiatric disorders/ coagulation abnormality Puncture site infection Orbital injury with ocular trauma Known structural orbital disease Patients with hypersensitivity to any of the local anaesthetics in use

Design outcomes

Primary

MeasureTime frame
Headache (Measured by Numeric Pain Rating Scale) Optic Nerve Sheath DiameterTimepoint: Pre Procedure 15 Minutes Post Procedure 6 Hours Post Procedure 12 Hours Post Procedure 24 Hours Post Procedure 48 Hours Post Procedure

Secondary

MeasureTime frame
Glasgow Coma Scale Mean Arterial Pressure Heart Rate Oxygen Saturation Timepoint: Pre Procedure 15 Minutes Post Procedure 6 Hours Post Procedure 12 Hours Post Procedure 24 Hours Post Procedure 48 Hours Post Procedure

Countries

India

Contacts

Public ContactDr. Dimple Shah

INSTITUTE OF NEUROSCIENCES. KOLKATA

drdimple10@gmail.com9123961462

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026