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Using Injectable Platelet-Rich Fibrin (i-PRF) to Treat Under-Eye Aging: A Clinical Study

A Prospective Study to Evaluate the Efficacy and Safety of Injectable Platelet-Rich Fibrin (i-PRF) in the Management of Periorbital Aging Changes: Clinical, Dermoscopic, and Patient-Reported Outcome Assessment. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/107424
Enrollment
25
Registered
2026-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

Datta Meghe Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adults aged 30 60 years with clinical signs of periorbital aging (e.g., fine lines, volume loss, and pigmentation). 2. Fitzpatrick skin types III V. 3. Willingness to get i-PRF injections and attend follow-up appointments. 4. Participants who agree to take part in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with active dermatological or systemic infections. 2. History of bleeding disorders or anticoagulant therapy. 3. Autoimmune diseases or immunosuppressed states. 4. History of cosmetic procedures (e.g., fillers, botulinum toxin) in the periorbital region in the past 6 months. 5. Pregnant or lactating women. 6. Known hypersensitivity to any materials used in the procedure. 7. Inability or unwillingness to comply with study protocol.

Design outcomes

Primary

MeasureTime frame
Improvement in periorbital aging changes assessed using the Wrinkle Severity Rating Scale (WSRS) and Visual Analog Scale (VAS).Timepoint: Baseline, 4 weeks, and 8 weeks.—

Secondary

MeasureTime frame
NILTimepoint: Nil—

Countries

India

Contacts

Public ContactManasi Mukund Joshi

Datta Meghe Medical College, Nagpur

drsabiha.derm@gmail.com8806294039

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026