Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous dexmedetomidine: Dexmedetomidine 1 microgram per kg diluted in 50 ml normal saline, 20 min prior to induction,infused over 10 min
Control Intervention1: Nebulized dexmedetom
Sponsors
Dr NAGARAJ
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 65 years of either gender with controlled hypertension 2.American Society Of Anaesthesiologists (ASA) physical status II patients 3.Patients posted for elective surgery under general anaesthesia requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: 1.Patient on beta blockers 2.Patients with Cardiac conduction abnormalities 3.Patients with severe hepatic, renal or respiratory dysfunction 4.Pregnant or lactating women 5.Patients with BMI more than 35 kg per meter square
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in hemodynamic response specifically heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure during laryngoscopy and endotracheal intubation.Timepoint: Baseline, after drug administration and post intubation at 1,3,5,7 and 10 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events such as bradycardia and hypotension and assessment of sedation levels using Ramsay Sedation ScaleTimepoint: From drug administration until 10 minutes post intubation | — |
Countries
India
Contacts
Public ContactDr NEETU CHAUDHARY
Dr. Baba Saheb Ambedkar Hospital and Medical college, Sector-6, Rohini, Delhi.
Outcome results
None listed