Comparing Laser Treatment With and Without Calcium-Based Varnish for Reducing Tooth Sensitivity: A Clinical Study

Efficacy of Diode Laser with Calcium Phosphate - Based Varnish and Diode Laser alone among patients with dentine hypersensitivity: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107306

Enrollment

Registered

2026-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K031- Abrasion of teeth

Interventions

Intervention1: Calcium Phosphate Based varnish : Composition- 5% sodium fluoride varnish enhanced with calcium-phosphate 1. Active Ingredient Sodium Fluoride (NaF) 5% Delivers 22,600 ppm fluoride i

Eligibility

Inclusion criteria

Inclusion criteria: (i) Patients of either sex with age greater than or equal to 18 years (ii) NCCL, with Tooth wear index score (TWI) 2, not requiring restorative treatment (iii) Preoperative VAS score greater than or equal to 2 (iv) Patients Willing to provide informed consent

Exclusion criteria

Exclusion criteria: (1) Teeth with caries, defective restorations, occlusal restorations, chipped teeth (ii) Deep periodontal pockets, periodontal surgery within 3 months, and patients with orthodontic appliance or bridge work (iii) Use of desensitizing paste in the last 3 month (iv) Patient on analgesics (v) Uncontrolled systemic disease. (vi) Persons with mental health issues. (vii) Pregnant or lactating females (viii) Patients undergone bleaching (ix) patients with a proven or suspected milk protein allergy allergy

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of Diode Laser with Calcium Phosphate-Based varnish and Diode Laser alone among patients with dentine hypersensitivity Evaluation of treatment outcome will be based on VAS Score. Timepoint: VAS scores immediately after treatment, 1, 3, 6 months inte	—

Secondary

Measure	Time frame
To compare the reduction in dentine hypersensitivity between male & female participants following treatment.Timepoint: Immediately after treatment, 1, 3, 6 months intervals	—

Countries

India

Contacts

Public ContactDr. Mridula Parameswaran

Govt.Dental college Thiruvananthapuram

shijidinakaran@gmail.com9895402488

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026