Comparison of two inhaled medicines (Dexmedetomidine and Ketamine) to reduce throat discomfort after placement of a breathing tube during surgery

A Comparative evaluation of Dexmedetomidine and Ketamine nebulization in preventing postoperative sore throat following endotracheal intubation - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107302

Enrollment

100

Registered

2026-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 50mcg with 4ml normal saline nebulisation over 20 minutes Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6:

Eligibility

Inclusion criteria

Inclusion criteria: ASA I to III patients undergoing general anaesthesia

Exclusion criteria

Exclusion criteria: ASA IV Pregnancy

Design outcomes

Primary

Measure	Time frame
Incidence and severity of postoperative sore throatTimepoint: 0, 2, 4, 8, 12 and 24 hours	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDevashri Vasudevan

SKS Hospital and Post Graduate Medical Institiute

gprabu_mmc@yahoo.co.in9884469456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026