Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex 1mg/kg: Study participants will be randomized into three groups.Intervention group will receive 1mg/kg of Inj. Sugammadex when the second Twitches to train of four stimulati
Sponsors
Rakshith C
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of either sex- male or female. 2.Patients of age group 18 to 60 years of Manipuri ethnicity undergoing elective laparoscopic cholecystectomy surgery under general anaesthesia. 3.Patients of American Society of Anaesthesiologists (ASA) physical status grade 1 or 2
Exclusion criteria
Exclusion criteria: 1.Patients not willing to participate. 2.Patients with known allergy to any of the study drugs. 3.Patients with known neuromuscular disease. 4.Patients with history of drug abuse (alcohol, sedative and analgesic 5.Patients with pre-existing conditions like respiratory, cardiovascular, hepatic or renal dysfunction etc 6.Patients with suspected malignant hyperthermia. 7.Pregnant and breast-feeding patients. 8.Patient who had joined in any studies in the past one month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time taken from the start of administration of the study drugs (Sugammadex) at appearance of second twitch of train of four stimulation till recovery of normalised TOF ratio of 0.9 or more. Timepoint: Hemodynamic parameters such as blood pressure and heart rate at 5 minutes, thereafter for every 10 minutes intraoperatively and immediate postoperative period till one hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the time taken to attain 5 seconds head lift from the start of administration of the study drug. Timepoint: Incidences of train of four normalised ratio of less than 0.9 during the first hour of postoperative period | — |
Countries
India
Contacts
Public ContactTakhelmayum Hemjit Singh
Regional Institute of Medical Sciences Imphal
Outcome results
None listed