A comparison of two drugs for treating low blood pressure after spinal anaesthesia in patients undergoing lower abdominal surgery

A comparative study of Intravenous Phenylephrine and Ephedrine Hydrochloride for treating post-spinal hypotension in Lower Abdominal Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107281

Enrollment

Registered

2026-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: intravenous Phenylephrine Hydrochloride: Phenylephrine Hydrochloride will be administered to cases of lower abdominal surgeries for post-spinal hypotension management Control Interventi

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I and II. 2. Undergoing elective lower abdominal surgeries under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. ASA physical status III and IV. 3. History of hypotension or cardiovascular diseases. 4. Patients on beta-blockers or with arrhythmias. 5. Bleeding disorders or on anticoagulant therapy. 6. Severe anaemia or cerebrovascular disease.

Design outcomes

Primary

Measure	Time frame
Intravenous phenylephrine hydrochloride restores systolic blood pressure more rapidly than intravenous ephedrine hydrochloride in patients with post-spinal hypotension during lower abdominal surgeriesTimepoint: Assessment will be done at 4 hours post-spinal duration.	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Neeta Chaudhary Verma

Datta Meghe Institute of Higher Education and Research

neetachaudhary1234@gmail.com8788378382

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026