Study to Compare Lidocaine Patch and Buprenorphine Patch for Pain Relief After Laparoscopic Gallbladder Surgery

A Randomized controlled study to compare the 5% Lidocaine patch, 5% Buprenorphine patch vs Placebo patch for postoperative analgesia in Laparoscopic cholecystectomy patients - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107279

Enrollment

105

Registered

2026-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis

Interventions

Intervention1: Lidocaine versus Buprenorphine versus placebo patch for post-operative analgesia: For post-operative analgesia using Lidocaine, Buprenorphine and a placebo patch on laparoscopic cholecy

Eligibility

Inclusion criteria

Inclusion criteria: Weight between 30-90kg Patients planned for elective laproscopic cholecystectomy surgeries

Exclusion criteria

Exclusion criteria: Patients with history of trauma, infection, surgery or chronic pain involving shoulders Patients with history of allergy to lidocaine or adhesive Patients with pregnancy or heart disease Patients with chronic abuse of opioids Patients with hypersensitivity to local anaesthetics Patients with impaired liver or renal dysfunction

Design outcomes

Primary

Measure	Time frame
To compare the duration of postoperative analgesia with application of transdermal Lidocaine patch, Buprenorphine patch vs Placebo patch as per visual analog scale(VAS) Score Timepoint: To compare the duration of postoperative analgesia with application of transdermal Lidocaine patch, Buprenorphine patch vs Placebo patch as per visual analog scale(VAS) Score	—

Secondary

Measure	Time frame
1. To compare the hemodynamic changes among three study groups a) Heart Rate (HR) b) Blood pressure (BP) c) Mean Arterial Pressure (MAP) 2. To evaluate the usage of rescue analgesic drugs in all the study groups. Timepoint:	—

Countries

India

Contacts

Public ContactMukesh Kumar G

Jawaharlal Nehru Medical College

syedkamranhabib@gmail.com9897172780

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026