Hyaluronic Acid mixed gelfoam versus Advanced PRF on postoperative sequelae after surgical extraction of lower third molars: A Split-Mouth Study

Effectiveness of intra- socket application of Hyaluronic Acid mixed gelfoam versus Advanced Platelet Rich Fibrin on postoperative sequelae after surgical extraction of lower third molars: A Split-Mouth Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/107264

Enrollment

Registered

2026-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Hyaluronic acid mixed gelfoam: Hyaluronic acid stimulates expression of growth factors by binding to their receptors thus accelerating healing process. It plays a key role in the proced

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients indicated for surgical removal of bilateral impacted mandibular third molars with equal surgical difficulty

Exclusion criteria

Exclusion criteria: Patients with systemic disorders that potentially impair the healing process, such as uncontrolled diabetes mellitus, history of radiotherapy or chemotherapy to the head and neck, smokers, and pregnant or lactating mother were excluded from the study.

Design outcomes

Primary

Measure	Time frame
-To access the pain using visual analogue scale (VAS) -To access the facial swelling -To evaluate the maximum interincisal opening (in mm) and access trismus.Timepoint: 1st, 3rd and 7th day postoperative.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Aakriti Kumari

Sardar Patel Post Graduate Institute of Dental and Medical Sciences

dr_amitgaur@yahoo.com9415330300

Outcome results