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New Clinical Trial Compares Traditional Light Therapy with Advanced Laser Combinations for Vitiligo Patients

Fractional CO2 LASER Plus NBUVB Versus NBUVB in Treatment of Refractory NonSegmental vitiligo: A Randomized Comparative Trial - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/107249
Enrollment
25
Registered
2026-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo

Interventions

Intervention1: CO2 LASER: Two treatment sessions will be administered at a 1month interval. A 10600 nm eCO2 laser ALMA will be used. Treatment parameters: Two passes were delivered using pulse energ

Sponsors

NRS MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 12 to 60 years. Both male and female patients. Stable vitiligo patients for at least 1 year. No improvement with other modes of treatment for the past 6months. Minimum of two nearly bilaterally symmetrical lesions

Exclusion criteria

Exclusion criteria: History of photosensitive conditions, keloids, or hypertrophic scars. Infection over the vitiligo patches. Pregnant or lactating females. History of skin cancer or bleeding tendencies. Received alternate treatment last 3 months.

Design outcomes

Primary

MeasureTime frame
To compare the treatment efficacy between fractional CO2 Laser plus NBUVB and NBUVB in refractory non-segmental vitiligoTimepoint: After 1 month of completion of last LASER session

Secondary

MeasureTime frame
To assess the epidemiology of resistant nonsegmental vitiligo To compare the safety & adverse effect between the two sides Side A CO2 LASER plus NBUVB & Side B NBUVB To assess association of other autoimmune diseases Timepoint: 1 month after completion of last LASER session

Countries

India

Contacts

Public ContactMahormi Mazumder

NRS Medical College and Hospital

achararun@rediffmail.com9434017410

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026