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Assessing Diaphragm Movement with Ultrasonography for Diagnosing Post Operative Muscle Weakness

Comparison Of Diaphragmatic Excursion And Diaphragmatic Thickening Fraction As Ultrasound Markers For Assessing Post Operative Residual Curarization - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/03/107212
Enrollment
70
Registered
2026-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J969- Respiratory failure, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

Melmaruvathur Adhiparasakthi Institute Of Medical Sciences and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 75 years. 2. American Society of Anesthesiologists (ASA) physical status I, II and III. 3. Patients undergoing elective surgery under general anaesthesia with non-depolarizing neuromuscular blocking agents. 4. Patients planned for extubation in the operating room. 5. Patients providing written informed consent for participation in the study.

Exclusion criteria

Exclusion criteria: Patients with known neuromuscular disorders or diaphragmatic dysfunction Body mass index more than 40 kg per meter square Patients undergoing thoracic or upper abdominal surgery Patients requiring postoperative mechanical ventilation Patients in whom adequate diaphragmatic ultrasound images cannot be obtained

Design outcomes

Primary

MeasureTime frame
To compare the diagnostic accuracy between Diaphragmatic Excursion(DE) and Diaphragmatic Thickening Fraction(DTF) in determining Postoperative residual curarization.Timepoint: DE and DTF will be measured at 4 timepoints, T1(first timepoint)- before induction of general anaesthesia, T2(second timepoint)- at reversal drug injection, T3(third timepoint)- 2minutes after extubation, T4(fourth timepoint)- 30minutes after extubation.—

Secondary

MeasureTime frame
1.To assess the correlation between ultrasound parameters & Train of Four (rTOF) ratios. 2.To evaluate the relationship between ultrasound findings & clinical respiratory outcomesTimepoint: at 4 timepoints, T1(first timepoint)- before induction of general anaesthesia, T2(second timepoint)- at reversal drug injection, T3(third timepoint)- 2minutes after extubation, T4(fourth timepoint)- 30minutes after extubation.—

Countries

India

Contacts

Public ContactKarthika Sivaprakash

Tamil Nadu Dr. MGR Medical University

vkeerthana01994@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026