The study is on efficacy and safety of OFA in geriatric patients undergoing lower thoracic and lumbar spine surgery. Patients more than 60 years age,ASA I II scheduled for surgery will be taken.primary outcome is better result in post op nrs score in ofa group.

THE STUDY ON OPIOID FREE ANESTHESIA TECHNIQUE VS OPIOID BASED ANESTHESIA TECHNIQUE FOR LOWER THORACIC AND LUMBAR SPINE SURGERY IN GERIATRIC PATIENTS. A PROSPECTIVE QUASI RANDOMIZED STUDY - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107171

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M511- Thoracic, thoracolumbar and lumbosacral intervertebral disc disorders with radiculopathy

Interventions

Intervention1: OPIOID FREE ANESTHESIA: o Induction: Dexmedetomidine (1 mcg/kg over 10 min), and propofol (2 mg/kg) o Maintenance: Dexmedetomidine infusion (0.5 mcg/kg/min ), TCI guided Propofol infusi

Eligibility

Inclusion criteria

Inclusion criteria: Patient giving consent for the study Age more or equal to 65 years ASA physical status 1 and 2 Scheduled for elective lower thoracic or lumbar spine surgery (T7-L5) No known opioid dependence or allergy to study drugs

Exclusion criteria

Exclusion criteria: Patients not giving consent for the study ASA III or IV Redo surgery MMSE less than 24 Chronic opioid use or history of substance abuse Cognitive impairment affecting pain assessment Contraindications to study drugs

Design outcomes

Primary

Measure	Time frame
Better Post operative NRS score till 24 hours.Timepoint: POST OPERATIVE TIME AT 0,2,4,6,8,12,24 HR	—

Secondary

Measure	Time frame
1 Lesser Cumulative requirement of rescue analgesia Intra and post operatively. 2 Lesser Time to extubate (end of surgery to end of ET tube removal) 3 Lesser Post operative cognitive dysfunction (1 hour after shifting in PACU) 4 Lesser Post operative sedation and agitation(1 hour after shifting in PACU) Timepoint: POST OPERATIVE TIME AT 0,2,4,6,8,12,24 HR	—

Countries

India

Contacts

Public ContactDR RIYA KAUSHAL

Dr Ram Manohar Lohia Institute Of Medical Sciences

shashian2014@gmail.com9935501163

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026