In patients undergoing a chest procedure for pleural disease, does applying suction to the chest tube improve removal of air or fluid compared to no suction.

To study the efficacy of addition of negative suction to chest drain post medical thoracoscopy in drainage of air/fluid compared with no suction - A single centered, open labelled, randomized control trial EFFISUC STUDY - EFFISUC STUDY

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107146

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J90-J94- Other diseases of the pleura

Interventions

Intervention1: Intercostal drainage tube connected to negative suction of -20cm H2O: Intercostal drainage tube is connected to negative suction of -20cm H2O using a manual vacuum controller in post me

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 18 years and above in whom intercostal drainage tube is inserted post diagnostic medical thoracoscopy

Exclusion criteria

Exclusion criteria: -Patients who are less than 18 years of age -Pregnant women -Those who have undergone talc poudrage at the time of medical thoracoscopy -Therapeutic Medical Thoracoscopy -Pleural effusion with USG showing septations of grade 3 and 4

Design outcomes

Primary

Measure	Time frame
To determine the mean time (in hours or days) taken for removal of chest drain following medical thoracoscopy, in patients managed with the addition of negative suction to the chest drain versus those managed without suction in the context of air or fluid drainage Timepoint: hours to days until the chest drain is fit for removal. Fit for chest drain removal 1.Complete lung expansion as determined by Chest Xray 2.No air leak 3.In patients where pleurodesis is planned, chest drain will be removed after pleurodesis. However, time taken for ICD removal will be calculated until the chest drain is fit for removal when both the criteria are met.	—

Measure

Time frame

To determine the mean time (in hours or days) taken for removal of chest drain following medical thoracoscopy, in patients managed with the addition of negative suction to the chest drain versus those managed without suction in the context of air or fluid drainage Timepoint: hours to days until the chest drain is fit for removal. Fit for chest drain removal 1.Complete lung expansion as determined by Chest Xray 2.No air leak 3.In patients where pleurodesis is planned, chest drain will be removed after pleurodesis. However, time taken for ICD removal will be calculated until the chest drain is fit for removal when both the criteria are met.

—

Secondary

Measure	Time frame
Proportion of patients with lung expansion in each group at the end of 4 hoursTimepoint: 4 hours;Total duration of hospital stay among patients in both groupsTimepoint: days;Adverse events among patients in both groupsTimepoint: not applicable	—

Countries

India

Contacts

Public ContactThomas Jeo Joseph

Christian Medical College

drricha21@gmail.com9600771705

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026