Health Condition 1: M266- Temporomandibular joint disorders
Conditions
Interventions
Control Intervention1: Intra articular autologous nanofat grafting: Autologous nanofat prepared from abdominal subcutaneous adipose tissue using standard emulsification technique and injected intra ar
Sponsors
Muhammed Jaseel S V
Eligibility
Inclusion criteria
Inclusion criteria: -Patients aged between 18 50 years -Patients with ASA class 1 and 2 physical status -Patients clinically diagnosed with disc displacement with reduction or disc displacement without reduction according to DC/TMD Axis I diagnostic criteria. -Patients who are refractory to conservative management for more than a period of 3 months. -Patients willing to undergo abdominal fat harvesting and intra-articular nanofat injection
Exclusion criteria
Exclusion criteria: -Local infection at donor or recipient site -Lactating or pregnant women -Previous Temporomandibular joint surgery or intra-articular injections within 6 months -Systemic steroid or immunosuppressive therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in TMJ pain intensity measured using Visual Analog Scale (VAS) and improvement in functional limitation assessed using Jaw Functional Limitation Scale (JFLS)Timepoint: Baseline,15 days, 1 month,3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in maximum mouth opening (mm)Timepoint: Baseline,15 days, 1 month,3 months;Improvement in lateral mandibular movements (mm)Timepoint: Baseline,15 days, 1 month,3 months | — |
Countries
India
Contacts
Public ContactMuhammed Jaseel S V
Yenepoya Dental College
Outcome results
None listed