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Evaluation of outcomes after TMJ lavage with and without platelet rich plasma

Comparative evaluation of clinical outcomes of arthrocentesis with and without platelet rich plasma in the management of internal derangement of TMJ - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/03/107129
Enrollment
20
Registered
2026-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M266- Temporomandibular joint disorders

Interventions

Intervention1: Arthrocentesis followed by PRP: Arthrocentesis with normal saline followed by prp in the TM joint Control Intervention1: Arthrocentesis: Arthrocentesis with normal saline alone

Sponsors

MAYANK MAHNOT
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient of either gender above 18 years of age. 2. Patient complaining of pain in TMJ during mandibular movements . 3. Patients with reduced mouth opening and/or difficulty in mouth opening with pain. 4. Patients refractory to conservative methods of treatments for at least 6 months. 5. Patients who are willing and have given consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients below 18 years of age. 2. Pregnant and lactating women. 3. Patient with chronic use of medication such as antihistaminic, nonsteroidal anti inflammatory drugs which would complicate evaluation of their postoperative response. 4. Patients with degenerative joint diseases. 5. Patients with any haematological disorders. 6. Patients with previous open TMJ surgery. 7. Patients with immunocompromised status.

Design outcomes

Primary

MeasureTime frame
The result of the present study will help us to know the effectiveness of using intra articular PRP injections along with arthrocentesis in management of internal derangements of TMJ.Timepoint: Evaluation will be done at baseline, 7th day, 1st month, 3rd month and 6th month respectively

Secondary

MeasureTime frame
The study results will be helpful in clinical applications of using PRP in Temporomandibular Disorders and hence can be used further in various research.Timepoint: 6 MONTHS

Countries

India

Contacts

Public ContactMayank Mahanot

GOVERNMENT DENTAL COLLEGE

bijupappachan2121@gmail.com8109006001

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026