Evaluate the effect of laser therapy on periodontal defects along with bone graft in an intervention group of participants and compare with the participants who received bone graft alone for periodontal defects

Effect of Low Level Laser Therapy on Treatment of Infrabony Defect with Bone Graft: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107117

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Low Level Laser Therapy with bone graft in an infrabony bone defect: After surgical debridement, the defect will be treated with low-level laser application as follows: Diode laser of w

Eligibility

Inclusion criteria

Inclusion criteria: Nearly bilateral symmetrical sites Defect with one tooth gap Patient with minimum of 20 permanent teeth with moderate to severe periodontitis Probing pocket depth more than or equal to 5mm with infrabony defect Systemically healthy patient

Exclusion criteria

Exclusion criteria: Medically compromised patients. Pregnant or lactating women. Smokers and tobacco users. Patient who had undergone surgical periodontal therapy at that site within 6 months. Patient on medication that affect bone healing

Design outcomes

Primary

Measure	Time frame
Radiographic parameters - Defect width, Defect depth and Defect fill Biochemical parameters - Periostin level in GCFTimepoint: Radiographic parameters - Defect width, Defect depth and Defect fill at baseline, 3 months and 6 months Biochemical parameters - Periostin level in GCF at baseline, 3 weeks, 3 months and 6 months	—

Secondary

Measure	Time frame
Plaque index (PI), Gingival index (GI), Periodontal Probing depth (PPD), Clinical attachment level (CAL)Timepoint: Baseline, 3 months and 6 months after surgery	—

Countries

India

Contacts

Public ContactDr Prerna Kataria

Uttar Pradesh University of Medical Sciences

drprernakataria@gmail.com9810120129

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026