Efficacy of Nanjaruppan Chooranam (Internal Medicine) and Arugan Thylam (External Medicine) for Treating Itchy Hives Kaanakadi (Urticaria) - A Clinical Trial

An Open Label Single Arm Clinical Trial to Evaluate the Effectiveness of Nanjaruppan Chooranam (Internal Medicine) and Arugan Thylam (External Medicine) in the management of Kaanakadi (Urticaria) among patients Reporting at Ayothidoss Pandithar Hospital, National Institute of Siddha - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107108

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L509- Urticaria, unspecified

Interventions

Intervention1: Nanjaruppan Chooranam: Internal Medicine: Dose:2 grams, Twice a day Adjuvant: Warm water Duration: 48 days Intervention2: Arugan Thylam: External application for 48 days Control Interve

Eligibility

Inclusion criteria

Inclusion criteria: Participants with urticaria UAS7 score between 7 to 27 based on at least three clinical symptoms of following Itching, Burning sensation, Erythema, Pale pink edematous wheal formation, Wheals surrounded by flare

Exclusion criteria

Exclusion criteria: Evidence of any skin condition other than urticaria, Angioedema, Narcotic addicts, Pregnancy and Lactation, Diabetic mellitus, Hypertension, Patients diagnosed with urticaria having a UAS7 score above 27 at baseline assessment

Design outcomes

Primary

Measure	Time frame
Significant reduction in clinical signs and symptoms of Urticaria based on Urticaria Activity Score over 7 days (UAS7) range from mild and moderate (7-27) to asymptomatic or (0-6) and changes in clinical laboratory blood parameters including IGE, AEC, ESR and CRP from baseline to post-treatmentTimepoint: 18 Months	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactProf Dr R Madhavan

National Institute of Siddha

drmadhavanji@gmail.com9965561656

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026