Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K311- Adult hypertrophic pyloric stenosis Health Condition 3: K742- Hepatic fibrosis with hepatic sclerosis
Conditions
Interventions
Intervention1: Oral care group: Twice daily brushing for 2 minutes starting 5 days preoperatively
Intervention2: Green tea group: Twice daily green tea intake 5 days preoperatively
Intervention3: Comb
Sponsors
AIIMS, Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: Patient of ASA grade I-III, elective major abdominal surgery (intra-peritoneal operation with no primary involvement of the thorax involving either luminal resection and/or resection of solid organ associated with gastro intestinal tract for duration at least 2 hours, Planned for general anesthesia with or without regional anesthesia and expected postoperative stay more than 5 days
Exclusion criteria
Exclusion criteria: pre existing delirium or dementia, severe hepatic or renal dysfunction, chronic psychiatric illness or patient taking antipsychotic drugs, patient with alcohol dependence or substance abuse, patients with regular consumption of more than 800 mg of caffeine per day (equivalent to 8 to10 cups of coffee), allergy to green tea or dental products, patient with a potential for pregnancy, breastfeeding, or childbirth, have language, vision, or hearing impairments that may compromise cognitive assessments, patient on melatonin and dexamethasone more than 8mg, patients needing more than 24 hours elective mechanical ventilation will be excluded post-randomization
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence ofpostoperative deliriumTimepoint: first 48 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare severity of postoperative deliriumTimepoint: first 48 hours after surgery;To evaluate duration of mechanical ventilationTimepoint: first 48 hours after surgery;To evaluate the ICU & hospital length of stayTimepoint: ;To explore postoperative respiratory adverse eventsTimepoint: first 48 hours after surgery;Quality of recoveryTimepoint: at 24 hours;To compare CRP and procalcitoninTimepoint: baseline, 3rd and 5th postoperative days;To compare oral microbiological floraTimepoint: at baseline and after 5 postoperative days;To determine bowel recovery following surgeryTimepoint: ;To determine possible adverse effects (e.g., caffeine-related effects, gastrointestinal irritation, mouthwash sensitivities)Timepoint: first 48 hours after surgery | — |
Countries
India
Contacts
Public ContactDevishree Das
All India Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed