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To study the ratios of blood levels of C-Reactive Protein and Albumin levels as prognostication of severe head injury patients and its association with outcomes in terms of neurological recovery.

Evaluation Of Serial CRP/Albumin Ratio (CAR) As Prognostic Marker For Severe Traumatic Brain Injury Patients And Its Association With Neurological Outcomes: A Prospective Observational Study (CAR-TBI study). - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/03/107080
Enrollment
197
Registered
2026-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil

Sponsors

Ankur Luthra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Isloated severe traumatic brain injury

Exclusion criteria

Exclusion criteria: Patients with known history of malignancy Patients with known history of hepatic dysfunction Patients with known history of severe metabolic disease Patients with known history of autoimmune disease

Design outcomes

Primary

MeasureTime frame
Correlation of serial CAR measurements on day 0, 2, 5 and 7 in severe TBI with 3-month neurological outcome using GOSE scaleTimepoint: 0, 48, 120 and 168 hours post ICU admission—

Secondary

MeasureTime frame
Describe Temporal CAR trends during the first week and generate a prognostic model using ROC curves.Timepoint: 0, 48, 120 and 168 hours post ICU admission;Correlate serial CAR values with admission GCS, length of ICU and hospital stay, mortality, neurological outcomes at discharge, duration of mechanical ventilation and other complications.Timepoint: At discharge from ICU and at 3 months post head injury—

Countries

India

Contacts

Public ContactAnkur Luthra

PGIMER, Chandigarh

zazzydude979@gmail.com7087008753

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026