A 12-Month Clinical Study Comparing Laser Teeth Whitening Using Regular Bleaching Chemicals and Chemical-Free Whitening Agents â?? Evaluating Tooth Colour Improvement and Tooth Sensitivity After Treatment

COMPARISON OF EFFICACY OF DIODE LASER VITAL TOOTH BLEACHING USING CONVENTIONAL PEROXIDE WITH THAT OF NON PEROXIDE AGENT FOR EVALUATION OF COLOUR CHANGE AND POST-OPERATIVE SENSITIVITY -A 12 MONTH FOLLOW UP RANDOMISED CLINICAL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107079

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K037- Posteruptive color changes of dental hard tissues

Interventions

Intervention1: DIODE LASER ASSISTED VITAL TOOTH BLEACHING: VITAL TOOTH BLEACHING WITH DIODE LASER ACTIVATION Control Intervention1: PEROXIDE AND NON PEROXIDE BLEACHING AGENT: COMPARE THE EFFICACY OF N

Eligibility

Inclusion criteria

Inclusion criteria: 1.Discoloured maxillary anterior teeth demonstrating a baseline colour shade greater than A2 on the Vita Classical Shade Guide. 2.Teeth confirmed to be vital on pulp sensibility testing. 3.Male and female participants aged 18 to 50 years. 4.Participants in good general health with satisfactory oral hygiene. 5.Teeth free from caries, cracks, restorations, periodontal disease, or structural defects. 6.Participants with no history of previous tooth bleaching procedures. 7.Absence of crowns, veneers, or full-coverage restorations on the teeth to be bleached.

Exclusion criteria

Exclusion criteria: 1. Teeth with periapical pathology evident on intraoral periapical radiograph (IOPAR). 2. Teeth presenting with hypersensitivity. 3. Participants with systemic conditions that could affect healing or pain perception. 4. Pregnant or breastfeeding individuals. 5. Teeth with moderate to severe fluorosis, tetracycline staining, or intrinsic stains unsuitable for vital bleaching. 6. Participants undergoing active orthodontic treatment. 7. History of orofacial tumors, trauma, or congenital tooth abnormalities affecting the study teeth. 8. Known allergy or hypersensitivity to bleaching agents or related materials

Design outcomes

Primary

Measure	Time frame
COLOUR CHANGE AND POSTOPERATIVE SENSITIVITYTimepoint: 1 week,3month,12 month follow up	—

Secondary

Measure	Time frame
pulpal responseTimepoint: 1 week,3month,12 month follow up	—

Countries

India

Contacts

Public ContactDR JAYASREE S

GOVERNMENT DENTAL COLLEGE KOZHIKODE

jsree21@yahoo.co.in9447276940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026