A study to evaluate the clinical effects of spinal dexmedetomidine versus clonidine as an adjuvant to hyperbaric levobupivacaine in surgeries below umblicus.

A study to evaluate the clinical effect of intrathecal dexmeditomidine versus clonidine as an adjuvant to hyperbaric levobupivacaine in infraumblical surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/03/107061

Enrollment

Registered

2026-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: effects of intrathecal dexmeditomidine as an adjuvant to hyperbaric levobupivacaine in infraumblical surgeries: After all aseptic preparation of back subarachnoid block will be given at

Eligibility

Inclusion criteria

Inclusion criteria: 2. ASA physical status I II 3. Patients undergoing elective infraumblical surgeries

Exclusion criteria

Exclusion criteria: 1. Patients on alpha adrenergic receptor blockers. 2. Local sepsis at the site of proposed puncture. 3. Patient with known hypersensitivity to study drug. 4. Patients being treated with anticoagulants, CNS active drugs. 5. Patients suffering from bleeding diathesis or coagulation disorders. 6. Spinal deformity or tuberculosis spine. 7. Increased intracranial pressure. 8. Patients with some psychiatric history. 9. Patients with neurological disease with motor and sensory deficit.

Design outcomes

Primary

Measure	Time frame
1.To study the clinical effects of Dexmedetomidine and Clonidine when used as adjuvants to intrathecal Levobupivacaine.Timepoint: To study the clinical effects of Dexmedetomidine and Clonidine when used as adjuvants to intrathecal Levobupivacaine. Every 2 minutes for the first 10 minutes, 5 minutes for the next 15 minutes and then at an interval of 15 minutes till the end of surgery. Then every 4 hourly for 24 hours	—

Measure

Time frame

1.To study the clinical effects of Dexmedetomidine and Clonidine when used as adjuvants to intrathecal Levobupivacaine.Timepoint: To study the clinical effects of Dexmedetomidine and Clonidine when used as adjuvants to intrathecal Levobupivacaine. Every 2 minutes for the first 10 minutes, 5 minutes for the next 15 minutes and then at an interval of 15 minutes till the end of surgery. Then every 4 hourly for 24 hours

—

Secondary

Measure	Time frame
1. To compare sensory & motor nerve block characteristics (onset, duration & recovery) in both groups. 2. To compare the duration of absolute analgesia & the time to first rescue analgesic in both the groups. 3. To compare hemodynamic parameters in perioperative period. 4. To evaluate the complications associated with intrathecal use of dexmedetomidine & clonidine. Timepoint: every 2 min for the first 10 minutes, 5 minutes for the next 15 minutes & then at an interval of 15 minutes till the end of surgery. Then every 4 hourly for 24 hours	—

Measure

Time frame

1. To compare sensory & motor nerve block characteristics (onset, duration & recovery) in both groups. 2. To compare the duration of absolute analgesia & the time to first rescue analgesic in both the groups. 3. To compare hemodynamic parameters in perioperative period. 4. To evaluate the complications associated with intrathecal use of dexmedetomidine & clonidine. Timepoint: every 2 min for the first 10 minutes, 5 minutes for the next 15 minutes & then at an interval of 15 minutes till the end of surgery. Then every 4 hourly for 24 hours

—

Countries

India

Contacts

Public ContactBHANUPREET KAUR

Adesh University, Bathinda

bhanupreet.768@gmail.com9855955768

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026